Approved research

Understanding the relationship between diet, nutrition and metabolic diseases

Lay summary

The relationship between diet, nutrition and metabolic diseases are still not clear. With the UK biobank data, We aim to: 1) investigate the relationship between dietary factors and metabolic diseases, such as diabetes, obesity and cardiovascular diseases. More importantly, we aim to clarify the causality of these relationships; 2) understand the reason behind the individual diverse response to the same dietary or nutritional factors, and develop personalized nutrition strategy based on one's genetic background to more efficiently prevent diseases. With these aims in mind, UKbiobank offers a great opportunity to provide solid evidence compared with other small scale studies. The results from our analyses will help advance our understanding about the relationship between diet and metabolic diseases, and potentially provide evidence to be taken by the dietary guideline.