Approved research

The Relationship Between Night Shift Work, Mental Health, and Thyroid Carcinoma: A Study in the UK Biobank

Lay summary

The Relationship Between Night Shift Work, Mental Health, and Thyroid Carcinoma: A Study in the UK Biobank

This research project aims to investigate the potential connection between long-term night shift work, mental health, and the risk of developing thyroid carcinoma. By analyzing data from the UK Biobank, a large biomedical database, we hope to shed light on this relationship and its implications for public health.

Previous studies have hinted at a correlation between night shift work, mental health issues, and thyroid disorders. However, the exact nature of this relationship remains unclear. Our study seeks to address this knowledge gap and provide a better understanding of the potential role of night shift work and mental health in the development of thyroid carcinoma.

To investigate this relationship, we will conduct a comprehensive analysis using data from the UK Biobank. This will involve adjusting for various factors that could influence the results, mainly focusing on long-term night-shifted work and mental health. Additionally, we will employ a technique called Mendelian randomization analysis, which uses genetic information to assess potential causal relationships. The project is expected to span a duration of approximately three years, including data collection, analysis, and interpretation.

Thyroid carcinoma is a significant public health concern, and understanding its risk factors is crucial for prevention and early detection. If our research confirms a significant association between night shift work, mental health, and thyroid carcinoma, it could have important implications for occupational health policies and practices. It may also highlight the need for targeted mental health support and interventions for individuals working night shifts. Ultimately, our findings could contribute to the development of strategies aimed at reducing the burden of thyroid carcinoma and improving the overall well-being of individuals working in night shift occupations.