Approved Research

Cardiovascular risk and risk prediction across all stages of chronic kidney disease in the UK Biobank cohort

Lay summary

Worldwide, around one in ten of the adult population has kidneys that do not work properly and are at high risk of having a heart attack or stroke. Most research has focused on preventing their kidney disease getting worse. Earlier research has shown that these patients do not always get the best treatment to lower their risk of getting heart disease or stroke. The aim of this research, which is expected to be finished within two and a half years, is to find out which patients are at particularly high risk of developing heart disease or stroke using information from the UK Biobank. The results can be used to make risk scores that doctors can use to find patients at high risk of heart disease or stroke and to make sure that they receive the best treatments to prevent these diseases. The ultimate goal is to improve survival and quality of life for people with kidney disease.