Approved Research

Cancer Genetics Variant Interpretation and Gene Discovery

Lay summary

Identifying people who are inherently at increased risk of developing cancer may lead to better standards of care through enhanced screening and treatment options. We plan to use the genetic data within UK Biobank to look for changes in genes that are more common in people with cancer compared to healthy individuals, assisted by merging the data with various in-house and external genetic and other data. These data will contribute to the activities of and be shared via CanGene-CanVar, a 5 year, 4.3 million Cancer Research UK Catalyst award program.