Approved research

Applying Deep Learning to Understand Disease-Genotype Relationships

Lay summary

A major outstanding question is how nature and nurture work together to impact human health. To bring new insights to this question, we are applying new artificial intelligence techniques to decipher the complex interactions between genes and environment. The broad data from the UK biobank is ideal for this approach, because artificial intelligence methods can find discoveries on their own in an unsupervised fashion, without requiring specific hypothesis. In line with the spirit of the UK Biobank's purpose of expanding biomedical research and discoveries, we will be publishing our discoveries to help advance human clinical genetics.